Isolated Intracranial Rosai-Dorfman Disease Mimicking Convexity Meningioma: A Case Report
نویسندگان
چکیده
Intracranial Rosai-Dorfman disease without systemic involvement is extremely rare. A 59-year-old woman presented with headaches. Magnetic resonance imaging revealed an enhancing posterior fossa convexity lesion with the dural tail sign. The preoperative diagnosis was meningioma. The histopathological examination revealed reactivity for S-100 and CD68 and non-reactivity for CD1a with emperipolesis (lymphophagocytosis) characteristic of Rosai-Dorfman disease. *Corresponding author: Dr. Tetsuro Sameshima, Department of Neurosurgery, NTT Medical Center Tokyo, 5-9-22, Higashi-Gotanda, Shinagawa-ku, Tokyo 141-8625, Japan, Tel: +81-3-3448-6111; Fax: +81-3-3448-6136; E-mail: [email protected] Received May 25, 2012; Accepted July 23, 2012; Published July 25, 2012 Citation: Sameshima T, Morita A, Tanikawa R, Tsuboi T, Kitai R (2012) Isolated Intracranial Rosai-Dorfman Disease Mimicking Convexity Meningioma: A Case Report. J Clin Exp Pathol 2:118. doi:10.4172/2161-0681.1000118 Copyright: © 2012 Sameshima T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
منابع مشابه
Isolated intracranial Rosai-Dorfman disease mimicking suprasellar meningioma: case report with review of the literature.
Rosai-Dorfman disease (RDD) is an idiopathic histiocytic proliferation affecting the lymph nodes. Isolated intracranial RDD is rare and usually appears as a well-defined, dural-based lesion without lymphadenopathy. The clinical and radiological features of intracranial RDD are similar to meningioma. Histopathology and immunohistochemistry are essential for a definitive diagnosis. This is a repo...
متن کامل1H-MR Spectroscopy in a Case of Isolated Intracranial Rosai-Dorfman Disease
A 61-year old female presented with a headache. CT and MR imaging showed a left frontal dural-based mass mimicking meningioma. H-MR spectroscopy showed elevated lipid peaks and decreased N-aspartate, choline and creatine peaks. No abnormal alanine peak was detected. The histological diagnosis was intracranial Rosai-Dorfman disease. Our case suggests that H-MR spectroscopy provides useful inform...
متن کاملIsolated intracranial rosai-dorfman disease involving the meninges: report of a rare case.
Sinus histiocytosis with massive lymphadenopathy or Rosai-Dorfman disease (RDD) is a reactive condition of unknown etiology, characterised by a proliferation of histiocytes exhibiting emperipolesis of lymphocytes and plasma cells. It usually presents as bilateral painless cervical lymphadenopathy. Extranodal RDD without nodal disease is seen in 23% of the cases. Intracranial RDD occurs in less ...
متن کاملIntracranial ROSAI-DORFMAN Disease
Rosai-Dorfman disease is a benign lymphohistiocytosis that often involve lymph nodes and present as massive lymphadenopathy with sinus histiocytosis. The disease is rarely associated with intracranial involvement. Herein, we report a 33-years-old man with recent onset of unconsciousness. According to his past medical history, he was suffering from frontal headache, ataxia and dizziness with no ...
متن کاملIsolated intracranial Rosai-Dorfman disease: report of two cases and a review of the literature.
Rosai-Dorfman disease (RDD) is a rare but well-recognized idiopathic histioproliferative disease affecting the systemic lymph nodes. It is characterized by an unusual proliferation of histiocytic cells. Intracranial localization is a rare manifestation of RDD. The clinical and radiological differentiation from meningiomas is difficult, and can only be achieved after histological examination. Th...
متن کامل